Rheumatoid Arthritis (RA) is an autoimmune disease in which the patient’s immune system generates cellular and antibody responses to various components of the joint such as type I collagen. As a result of this immune response, not only does joint destruction occur, but also other secondary complications such as pulmonary fibrosis, renal damage, and even heart damage.
Scientists are currently studying the effect of adult stem cell therapy on patients diagnosed with Rheumatiod Arthritis. Because Rheumatoid Arthritis complications include inflammation and tissue damage adult stem cells may target inflamed areas of the body and produce anti-inflammatory agents. we are also studying the stem cells ability to produce Regulatory T cells, a type of immune cell whose responsibility is to regulate the immune system while maintaining tolerance to self-antigens. By differentiating into these types of healthy cells there is hope that adult mesenchymal cells will be able to address the complications caused by Rheumatoid Arthritis.
How can Stem Cell Help?
- Currently, RA is treated with immune suppressive agents such as steroids, methothrexate, cyclosporine, and Remicade. These drugs show temporary relief but have long-term adverse effects due to non-specific inhibition of immune responses. These treatments do not address the issue of damage that has already occurred to the joints or extra-articular tissues.
- Stem cell treatment addresses the inflammation of the joint by repairing the synovial membrane by producing anti inflammatory agents.
- The objective is to restore the function and help improve the quality of life of the patient by reduction in pain and damage of the joints.
- The objective of treatment is to repair, reactivate and restore the functions of the joints in the body.
- The treatment aims to Suppress the immune reaction by producing regulatory T cells, a type of immune cell whose responsibility is to regulate the immune system while maintaining tolerance to self-antigens.
- Nature’s own way repairing impaired cells and tissues.
- Simple but very effective.
- Low or no risk of tumors or other side effects.
- Bone marrow derived mesenchyme stem cells are capable of creating all the cells making the immune system.
- Lower overall risk of treatment.